Policy BriefInternational Consensus2014
Community management of opioid overdose (WHO guideline)
World Health Organization
WHO clinical guideline recommending wide community distribution of take-home naloxone alongside overdose education.
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Evidence Library
A curated, source-verified library of the strongest available research on harm reduction, treatment outcomes, overdose prevention, and the comparative effectiveness of voluntary versus coercive addictions care. Every entry links to a peer-reviewed journal, government report, university source, or major public-health agency.
Overdose Prevention
Evidence on naloxone, supervised consumption services, drug-checking, and outreach.
Evidence
Region
Showing 11 of 11 entries
- Policy BriefInternational
SAMHSA Opioid Overdose Prevention Toolkit
SAMHSA (US)
Federal US toolkit summarizing evidence and operational guidance for naloxone distribution, prescriber education, and survivor follow-up.
- Policy BriefInternational
Naloxone DrugFacts
National Institute on Drug Abuse (NIH)
NIDA research summary on naloxone formulations, evidence base, and program design.
- Government ReportCanada
Drug Checking Project — quarterly findings
BC Centre on Substance Use
Quarterly publication on FTIR/strip drug-checking data across BC; documents fentanyl contamination across the unregulated supply.
- Policy BriefCanada
Take Home Naloxone programs across Canada
CATIE / Public Health Agency of Canada
Pan-Canadian summary of provincial take-home naloxone programs, eligibility, and distribution channels.
- Economic AnalysisInternational2022
Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics
The Lancet Public Health · Irvine MA, Oller D, Boggis J, et al.
Modelling study estimating very high naloxone-leave-behind needs in the fentanyl era; supports widespread distribution.
- Policy BriefCanada
Supervised consumption services in Canada: an evidence summary
Canadian Centre on Substance Use and Addiction
Evidence brief summarizing supervised consumption site models, outcomes, benefits, concerns, and Canadian policy context.
- Systematic ReviewInternational2024
Fentanyl Test Strips for Harm Reduction: A Scoping Review
Public Health Reports · Reed MK, Salcedo VJ, Guth A, et al.
Reviews studies of fentanyl test strip use among people who use drugs: high uptake, behaviour change, no observed harm.
- Cohort StudyInternational Consensus2010
What can we learn from the Portuguese decriminalisation of illicit drugs?
British Journal of Criminology · Hughes CE, Stevens A
Evaluates Portugal's 2001 decriminalisation: sharp drops in HIV, drug-related deaths, and incarceration without an increase in problematic drug use.
- Meta-analysisInternational Consensus2025
Effectiveness of naloxone distribution in community settings to reduce opioid overdose deaths among people who use drugs: a systematic review and meta-analysis
BMC Public Health (CDC) · Fischer LS, et al.
Meta-analysis pooling survival outcomes for community OEND programs across people who use drugs, family/community members, and police.
98.3% survival when naloxone was administered by peers who use drugs; 95.0% by family/community; 92.4% by police.
- Policy BriefCanada Consensus2024
Supervised Consumption Sites — Evidence Brief
Canadian Centre on Substance Use and Addiction (CCSA)
National aggregation of Canadian SCS data on overdose reversals, health-service linkages, and community impact.
January 2017 – May 2024: SCS staff reversed 58,444+ overdoses with zero on-site fatalities Canada-wide.
Curated and maintained by Voluntary Treatment First Saskatchewan. Every entry links to a peer-reviewed journal, government report, university, or major public-health agency. Spot a broken link or missing study? Let us know.